Glucose 6 Phosphate Dehydrogenase Deficiency Diet
Typically these symptoms subside once the patient removes the trigger, but in some cases it can result in chronic anemia. Hemolytic crises are more common in children and triggers include certain illnesses or painkillers. Mothballs can also cause extremely harmful if a child ingests one ( x). Diabetic Ketoacidosis Diabetic ketoacidosis is when the body produces excess acids in the blood called ketones. It a common complication associated with diabetes, which is why some patients may overlook it when it comes to G6PD deficiency. Both conditions can also have some of the same triggers ( x). G6PD Deficiency Triggers G6PD deficiency is a genetic condition that results from gene mutations. However, there are several factors that researchers also recognize as "causes" or, more accurately, triggers of this rare condition. These factors cause oxidative stress in the body. Food The foods people eat affect every part of their bodies, including the blood. This means that certain foods can even trigger G6PD symptoms.
Glucose 6 phosphate dehydrogenase deficiency diet book
First and foremost is fava beans. However, some patients also cannot tolerate blueberries, red wine, soybeans and tonic water ( x). Medications There are also several medications that may trigger symptoms in patients with a deficiency. These medications may thin the blood and break down red blood cells. Medications like antibiotics, anticonvulsants, antimalarial and cardiovascular drugs may cause adverse reactions in the blood. Certain medication designed to treat cancer may also cause adverse reactions ( x). Viral & Bacterial Infections Bacterial and viral infections may also trigger G6PD symptoms. If a patient has an infection, it causes oxidative stress that the body cannot tolerate as well. For example, bacterial infections that may trigger symptoms include strep throat, tuberculosis and urinary tract infections. Viral infections include chickenpox, AIDS and the common cold and flu ( x). G6PD Deficiency Treatment Blood Transfusion G6PD is manageable and patients can live with the condition, but in some rare cases it may require treatment to reverse abnormalities in the blood.
For example, in severe cases patients may need a blood transfusion. This is a common practice and typically it is very safe. In the process, the physician transfers blood from a donor to the recipient's bloodstream ( x). Dialysis Dialysis is a treatment that helps support kidney function if they cannot perform correctly on their own. The kidneys help remove waste, salt and extra water from the body. They can also help the body maintain a safe level of certain chemicals in the blood that it needs, such as potassium and sodium. Lastly, dialysis may help control high blood pressure, which medical researchers associate with kidney failure. In fact, acute renal failure is common in patients with G6PD deficiency and patients may need to undergo dialysis to manage it ( x). Avoid Stressors Although there are treatment options, the best way for patients with G6PD deficiency to avoid symptoms is to avoid triggers. The three main triggers are medication, food and infections. Patients should take extra precaution to avoid any factors that can cause oxidative stress ( x).
(2018). In Jameson JL, et al. (Ed. ), Harrison's Principles of Internal Medicine (20th ed. Vol 1, pp 714-717). New York, NY: McGraw-Hill. Glader, B. (2019). Genetics and pathophysiology of glucose-6-phosphate dehydrogenase (G6PD) deficiency. UpToDate. Retrieved September 1, 2020, from Glader, B. (2020). Diagnosis and management of glucose-6-phosphate dehydrogenase (G6PD) deficiency. Retrieved September 2, 2020, from
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