11:38 Lipotrim Training Webinar, Principles of Weight Management - Part 1 - Body Mass Index (BMI) Lipotrim UK Views 239 Year ago Body Mass Index (BMI) has been used for decades by the World Health Organisation (WHO) as a standard for recording obesity... Next
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The answer to the puzzle was discovered in 1967. Harvard researchers famously stuck catheters into the brains of obese subjects who had been fasting for over a month, and discovered that ketones had replaced glucose as the preferred fuel for the brain. Your liver can turn fat into ketones, which can then breach the blood-brain barrier and sustain your brain if you're not getting enough carbohydrates. Switching fuels has such an effect on brain activity that it has been used to treat epilepsy since antiquity. The prescription of fasting for the treatment of epileptic seizures dates back to Hippocrates. In the Bible, Jesus seems to have concurred. To this day, it's unclear why switching from blood sugar to ketones as a primary fuel source has such a dampening effect on brain overactivity. How long can you fast, though? To prolong the fasting therapy, in 1921 a distinguished physician scientist at the Mayo Clinic suggested trying what he called a "ketogenic diet, " a high-fat diet designed to be so deficient in carbohydrates it could effectively mimic the fasting state.