Restricting carbohydrate may be an option for persons seeking to lose weight and reduce cardiovascular risk factors. Primary funding source: National Institutes of Health. Figures Appendix Figure Predicted mean changes in lean mass, total cholesterol level, LDL cholesterol level, HDL cholesterol level, and 10-y Framingham risk score in the low-fat and low-carbohydrate diet groups Results are from random-effects models and are expressed as means, with error bars representing 95% CIs. To convert cholesterol values to mg/dL, divide by 0. 0259. HDL = high-density lipoprotein; LDL = low-density lipoprotein. * P < 0. 05 for between-group difference. Figure 1. Study flow diagram * Five participants in the low-fat group and 6 in the low-carbohydrate group had no data on body weight at randomization. Figure 2. Predicted mean changes in body weight, fat mass, total–HDL cholesterol ratio, and triglyceride level in the low-fat and low-carbohydrate diet groups Results are from random-effects models and are expressed as means, with error bars representing 95% CIs.
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