[3] Leonard Bernstein was one of Thompson's students both at Harvard and at Curtis, according to his own testimony in a speech he gave at Curtis Institute's 75th Anniversary Banquet. Thompson's other notable students include Samuel Adler, Leo Kraft, Juan Orrego-Salas, John Davison, Thomas Beveridge, Charles Edward Hamm, George Lynn, William P. Perry, Christopher King, Joel Cohen, Frederic Rzewski, Richard Edward Wilson, John Walter Hill, and David Borden. In honor of Thompson's vast influence on male choral music, on May 2, 1964 he became the first recipient of the prestigious University of Pennsylvania Glee Club Award of Merit. [4] Established in 1964, this award sought "to bring a declaration of appreciation to an individual each year that has made a significant contribution to the world of music and helped to create a climate in which our talents may find valid expression. " He was also a recipient of Yale University 's Sanford Medal.
We anticipate that the developed synthetic ecosystem will serve in the future as a basis for the generation of testable hypotheses and as a scaffold for integrating and interpreting-omics data from experimental co-cultures. Copyright The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY 4. 0 International license.
Other things I did for my -10kg challenge As I live in Bali, you have to know that people eat rice twice a day here, and rice is just full or carbs, which I tend to avoid in February (only had it once in 2 weeks). Eating more fruits and vegetable. Which is also easy when you live in Bali, as there is a ton of option of green stuff, countless varieties of fruits, etc. I also track every single food that enters my body in order to increase the awareness I have about my food intake. I do it through pictures of my meals and writing down in a journal before sleeping. Practising yoga 2*1h30 a week, which also helps achieving a lot of other goals, especially flexibility wise. Take it easy Intermittent fasting is the simplest most efficient way I have ever seen so far to loose fat and increase performance in such a short amount of time. Even if it seems like I am very serious about it, I also take it easy when I can't make it. It's fine to make an exception sometimes when you can't eat as early as you planned, or when you end up eating 3x more than you wanted, etc.
We anticipate that the developed synthetic ecosystem will serve in the future as a basis for the generation of testable hypotheses and as a scaffold for integrating and interpreting -omics data from experimental co-cultures. Download data Downloaded 526 times Download rankings, all-time: Site-wide: 52, 536 In systems biology: 1, 206 Year to date: Site-wide: 87, 044 Since beginning of last month: Site-wide: 109, 996 Altmetric data Downloads over time Distribution of downloads per paper, site-wide
Marine ecosystems are characterized by an intricate set of interactions among their representatives. One of the most important occurs through the exchange of dissolved organic matter (DOM) provided by phototrophs and used by heterotrophic bacteria as their main carbon and energy source. This metabolic interaction represents the foundation of the entire ocean food-web. Here we have assembled a synthetic ecosystem to assist the systems-level investigation of this biological association. This was achieved building an integrated, genome-scale metabolic reconstruction using two model organisms (a diatom Phaeodactylum tricornutum and an heterotrophic bacterium, Pseudoalteromonas haloplanktis) to explore and predict their metabolic interdependencies. The model was initially analysed using a constraint-based approach (Flux Balance Analysis, FBA) and then turned into a dynamic (dFBA) model to simulate a diatom-bacteria co-culture and to study the effect of changes in growth parameters on such a system.
Finally, we developed a simpler dynamic ODEs system that, fed with dFBA results, was able to qualitatively describe this synthetic ecosystem and allowed performing stochastic simulations to assess the effect of noise on the overall balance of this co-culture. We show that our model recapitulates known metabolic cross-talks of a phototroph-heterotroph system, including mutualism and competition for inorganic ions (i. e. phosphate and sulphate). Further, the dynamic simulation predicts realistic growth rate for both the diatom and the bacterium and a steady state balance between diatom and bacterial cell concentration that matches those determined in experimental co-cultures. This steady state, however, is reached following an oscillatory trend, a behaviour that is typically observed in the presence of metabolic co-dependencies. Finally, we show that, at high diatom/bacteria cell concentration ratio, stochastic fluctuations can lead to the extinction of bacteria from the co-culture, causing the explosion of diatom population.
New Results doi: Abstract Marine ecosystems are characterized by an intricate set of interactions among their representatives. One of the most important occurs through the exchange of dissolved organic matter (DOM) provided by phototrophs and used by heterotrophic bacteria as their main carbon and energy source. This metabolic interaction represents the foundation of the entire ocean food-web. Here we have assembled a synthetic ecosystem to assist the systems-level investigation of this biological association. This was achieved building an integrated, genome-scale metabolic reconstruction using two model organisms (a diatom Phaeodactylum tricornutum and an heterotrophic bacterium, Pseudoalteromonas haloplanktis) to explore and predict their metabolic interdependencies. The model was initially analysed using a constraint-based approach (Flux Balance Analysis, FBA) and then turned into a dynamic (dFBA) model to simulate a diatom-bacteria co-culture and to study the effect of changes in growth parameters on such a system.